In cases of pure anterograde amnesia, patients have recollections of events prior to the injury, but cannot recall day-to-day information or new facts presented to them after the injury occurred. Usually, some capacity for learning remains, although it may be very elementary. In the other case, which has been studied extensively since the early 1970s, patients often have permanent damage, although some recovery is possible, depending on the nature of the pathophysiology. In the case of drug-induced amnesia, it may be short-lived and patients can recover from it. Some with severe cases have a combined form of anterograde and retrograde amnesia, sometimes called global amnesia. People with anterograde amnesic syndromes may present with widely varying degrees of forgetfulness. To a large degree, anterograde amnesia remains a mysterious ailment because the precise mechanism of storing memories is not yet well understood, although it is known that the regions of the brain involved are certain sites in the temporal cortex, especially in the hippocampus and nearby subcortical regions. Both can occur together in the same patient. This is in contrast to retrograde amnesia, where memories created prior to the event are lost while new memories can still be created. In neurology, anterograde amnesia is the inability to create new memories after the event that caused amnesia, leading to a partial or complete inability to recall the recent past, while long-term memories from before the event remain intact.
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